NMR Studies on [ 2 + 3 ] Cycloaddition of Nitrile Oxides to Polyunsaturated Medium Size Rings
نویسنده
چکیده
Site selectivity, regioselectivity and stereoselectivity of [2 + 3] cycloaddition of 4-trifluoromethylbenzonitrile oxide to polyunsaturated medium size rings including 1,5,9-cyclododecatriene, 11-membered sesquiterpenes, 1,3-cyclooctadiene and 5-vinyl-2norbornene were examined. Site selectivity was correlated with electron charges of alkenyl carbon atoms. Structure of the products has been established by an extensive application of 1D and 2D H and C nuclear magnetic resonance (NMR) spectroscopy and electrospray ionization mass spectrometry. Some of the obtained products showed moderate fungicidal activities.
منابع مشابه
1,3-Dipolar Cycloaddition Reaction of Nitrile Oxides to Isatin Imines
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